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Class II histone deacetylases require P/Q-type Ca(2+) channels and CaMKII to maintain gamma oscillations in the pedunculopontine nucleus
Epigenetic mechanisms (i.e., histone post-translational modification and DNA methylation) play a role in regulation of gene expression. The pedunculopontine nucleus (PPN), part of the reticular activating system, manifests intrinsic gamma oscillations generated by voltage-dependent, high threshold N...
Autores principales: | Urbano, Francisco J., Bisagno, Verónica, Mahaffey, Susan, Lee, Sang-hun, Garcia-Rill, Edgar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120910/ https://www.ncbi.nlm.nih.gov/pubmed/30177751 http://dx.doi.org/10.1038/s41598-018-31584-2 |
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