A platform for phenotypic discovery of therapeutic antibodies and targets applied on Chronic Lymphocytic Leukemia

Development of antibody drugs against novel targets and pathways offers great opportunities to improve current cancer treatment. We here describe a phenotypic discovery platform enabling efficient identification of therapeutic antibody-target combinations. The platform utilizes primary patient cells...

Descripción completa

Detalles Bibliográficos
Autores principales: Ljungars, A., Mårtensson, L., Mattsson, J., Kovacek, M., Sundberg, A., Tornberg, U-C., Jansson, B., Persson, N., Emruli, V. Kuci, Ek, S., Jerkeman, M., Hansson, M., Juliusson, G., Ohlin, M., Frendéus, B., Teige, I., Mattsson, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120912/
https://www.ncbi.nlm.nih.gov/pubmed/30182064
http://dx.doi.org/10.1038/s41698-018-0061-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120912/
https://www.ncbi.nlm.nih.gov/pubmed/30182064
http://dx.doi.org/10.1038/s41698-018-0061-2

Ejemplares similares