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Inhibiting Multiple Deubiquitinases to Reduce Androgen Receptor Expression in Prostate Cancer Cells

Prostate cancer (PCa), a leading cause of cancer-related death in men, becomes resistant to androgen deprivation therapy by inducing androgen receptor (AR) activity, which is known as castration-resistant PCa (CRPC). Enzalutamide is an approved drug that inhibits AR activity and increases overall su...

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Detalles Bibliográficos
Autores principales: de las Pozas, Alicia, Reiner, Teresita, De Cesare, Virginia, Trost, Matthias, Perez-Stable, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120934/
https://www.ncbi.nlm.nih.gov/pubmed/30177856
http://dx.doi.org/10.1038/s41598-018-31567-3