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Minipuberty and Sexual Dimorphism in the Infant Human Thymus

AIRE expression in thymus is downregulated by estrogen after puberty, what probably renders women more susceptible to autoimmune disorders. Here we investigated the effects of minipuberty on male and female infant human thymic tissue in order to verify if this initial transient increase in sex hormo...

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Detalles Bibliográficos
Autores principales: Moreira-Filho, Carlos Alberto, Bando, Silvia Yumi, Bertonha, Fernanda Bernardi, Ferreira, Leandro Rodrigues, Vinhas, Christiana de Freitas, Oliveira, Lucila Habib Bourguignon, Zerbini, Maria Claudia Nogueira, Furlanetto, Glaucio, Chaccur, Paulo, Carneiro-Sampaio, Magda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120939/
https://www.ncbi.nlm.nih.gov/pubmed/30177771
http://dx.doi.org/10.1038/s41598-018-31583-3