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The mitotic spindle is chiral due to torques within microtubule bundles

Mitosis relies on forces generated in the spindle, a micro-machine composed of microtubules and associated proteins. Forces are required for the congression of chromosomes to the metaphase plate and their separation in anaphase. However, besides forces, torques may exist in the spindle, yet they hav...

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Detalles Bibliográficos
Autores principales: Novak, Maja, Polak, Bruno, Simunić, Juraj, Boban, Zvonimir, Kuzmić, Barbara, Thomae, Andreas W., Tolić, Iva M., Pavin, Nenad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120957/
https://www.ncbi.nlm.nih.gov/pubmed/30177685
http://dx.doi.org/10.1038/s41467-018-06005-7