Dexmedetomidine Attenuates Neuropathic Pain by Inhibiting P2X7R Expression and ERK Phosphorylation in Rats

α2-Adrenoceptor agonists attenuate hypersensitivity under neuropathic conditions. However, the mechanisms underlying this attenuation remain largely unknown. In the present study, we explored the potential roles of purinergic receptor 7 (P2X7R)/extracellular signal-regulated kinase (ERK) signaling i...

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Detalles Bibliográficos
Autores principales: Lin, Jia-Piao, Chen, Chao-Qin, Huang, Ling-Er, Li, Na-Na, Yang, Yan, Zhu, Sheng-Mei, Yao, Yong-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120967/
https://www.ncbi.nlm.nih.gov/pubmed/30181689
http://dx.doi.org/10.5607/en.2018.27.4.267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120967/
https://www.ncbi.nlm.nih.gov/pubmed/30181689
http://dx.doi.org/10.5607/en.2018.27.4.267

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