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Chimeric Proteins Containing MAP-1 and Functional Domains of C4b-Binding Protein Reveal Strong Complement Inhibitory Capacities

The complement system is a tightly regulated network of proteins involved in defense against pathogens, inflammatory processes, and coordination of the innate and adaptive immune responses. Dysregulation of the complement cascade is associated with many inflammatory disorders. Thus, inhibition of th...

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Detalles Bibliográficos
Autores principales: Hertz, Cecilie E., Bayarri-Olmos, Rafael, Kirketerp-Møller, Nikolaj, van Putten, Sander, Pilely, Katrine, Skjoedt, Mikkel-Ole, Garred, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120983/
https://www.ncbi.nlm.nih.gov/pubmed/30210498
http://dx.doi.org/10.3389/fimmu.2018.01945