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Chimeric Proteins Containing MAP-1 and Functional Domains of C4b-Binding Protein Reveal Strong Complement Inhibitory Capacities
The complement system is a tightly regulated network of proteins involved in defense against pathogens, inflammatory processes, and coordination of the innate and adaptive immune responses. Dysregulation of the complement cascade is associated with many inflammatory disorders. Thus, inhibition of th...
Autores principales: | Hertz, Cecilie E., Bayarri-Olmos, Rafael, Kirketerp-Møller, Nikolaj, van Putten, Sander, Pilely, Katrine, Skjoedt, Mikkel-Ole, Garred, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120983/ https://www.ncbi.nlm.nih.gov/pubmed/30210498 http://dx.doi.org/10.3389/fimmu.2018.01945 |
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