Host Restriction Factors APOBEC3G/3F and Other Interferon-Related Gene Expressions Affect Early HIV-1 Infection in Northern Pig-Tailed Macaque (Macaca leonina)

The northern pig-tailed macaques (NPMs) lack TRIM5α, an antiviral restriction factor, and instead have TRIM5-CypA. In our previous study, we demonstrated that HIV-1(NL4−3) successfully infected NPMs and formed a long-term viral reservoir in vivo. However, the HIV-1-infected NPMs showed relatively hi...

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Detalles Bibliográficos
Autores principales: Pang, Wei, Song, Jia-Hao, Lu, Ying, Zhang, Xiao-Liang, Zheng, Hong-Yi, Jiang, Jin, Zheng, Yong-Tang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120991/
https://www.ncbi.nlm.nih.gov/pubmed/30210504
http://dx.doi.org/10.3389/fimmu.2018.01965

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120991/
https://www.ncbi.nlm.nih.gov/pubmed/30210504
http://dx.doi.org/10.3389/fimmu.2018.01965

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