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BLTR1 in Monocytes Emerges as a Therapeutic Target For Vascular Inflammation With a Subsequent Intimal Hyperplasia in a Murine Wire-Injured Femoral Artery

Given the importance of high-mobility group box 1 (HMGB1) and 5-lipoxygenase (5-LO) signaling in vascular inflammation, we investigated the role of leukotriene signaling in monocytes on monocyte-to-macrophage differentiation (MMD) induced by HMGB1, and on vascular inflammation and subsequent intimal...

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Detalles Bibliográficos
Autores principales: Baek, Seung E., Park, So Y., Bae, Sun S., Kim, Koanhoi, Lee, Won S., Kim, Chi D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121004/
https://www.ncbi.nlm.nih.gov/pubmed/30210495
http://dx.doi.org/10.3389/fimmu.2018.01938