The McGill Transgenic Rat Model of Alzheimer's Disease Displays Cognitive and Motor Impairments, Changes in Anxiety and Social Behavior, and Altered Circadian Activity

The McGill-R-Thy1-APP transgenic rat is an animal model of the familial form of Alzheimer's disease (AD). This model mirrors several neuropathological hallmarks of the disease, including the accumulation of beta-amyloid and the formation of amyloid plaques (in homozygous animals only), neuroinf...

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Detalles Bibliográficos
Autores principales: Petrasek, Tomas, Vojtechova, Iveta, Lobellova, Veronika, Popelikova, Anna, Janikova, Martina, Brozka, Hana, Houdek, Pavel, Sladek, Martin, Sumova, Alena, Kristofikova, Zdenka, Vales, Karel, Stuchlík, Ales
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121039/
https://www.ncbi.nlm.nih.gov/pubmed/30210330
http://dx.doi.org/10.3389/fnagi.2018.00250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121039/
https://www.ncbi.nlm.nih.gov/pubmed/30210330
http://dx.doi.org/10.3389/fnagi.2018.00250

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