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Mechanism of BDNF Modulation in GABAergic Synaptic Transmission in Healthy and Disease Brains

In the mature healthy mammalian neuronal networks, γ-aminobutyric acid (GABA) mediates synaptic inhibition by acting on GABA(A) and GABA(B) receptors (GABA(A)R, GABA(B)R). In immature networks and during numerous pathological conditions the strength of GABAergic synaptic inhibition is much less pron...

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Detalles Bibliográficos
Autores principales: Porcher, Christophe, Medina, Igor, Gaiarsa, Jean-Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121065/
https://www.ncbi.nlm.nih.gov/pubmed/30210299
http://dx.doi.org/10.3389/fncel.2018.00273