Up-Regulation of TLR7-Mediated IFN-α Production by Plasmacytoid Dendritic Cells in Patients With Systemic Lupus Erythematosus

Objectives: Aberrant and persistent production of interferon-α (IFN-α) by plasmacytoid dendritic cells (pDCs) is known to play a key role in the pathogenesis of systemic lupus erythematosus (SLE). To assess the precise function of pDCs in SLE patients, we investigated the differential regulation of...

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Detalles Bibliográficos
Autores principales: Sakata, Kei, Nakayamada, Shingo, Miyazaki, Yusuke, Kubo, Satoshi, Ishii, Akina, Nakano, Kazuhisa, Tanaka, Yoshiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121190/
https://www.ncbi.nlm.nih.gov/pubmed/30210502
http://dx.doi.org/10.3389/fimmu.2018.01957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121190/
https://www.ncbi.nlm.nih.gov/pubmed/30210502
http://dx.doi.org/10.3389/fimmu.2018.01957

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