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Up-Regulation of TLR7-Mediated IFN-α Production by Plasmacytoid Dendritic Cells in Patients With Systemic Lupus Erythematosus

Objectives: Aberrant and persistent production of interferon-α (IFN-α) by plasmacytoid dendritic cells (pDCs) is known to play a key role in the pathogenesis of systemic lupus erythematosus (SLE). To assess the precise function of pDCs in SLE patients, we investigated the differential regulation of...

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Detalles Bibliográficos
Autores principales:	Sakata, Kei, Nakayamada, Shingo, Miyazaki, Yusuke, Kubo, Satoshi, Ishii, Akina, Nakano, Kazuhisa, Tanaka, Yoshiya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121190/ https://www.ncbi.nlm.nih.gov/pubmed/30210502 http://dx.doi.org/10.3389/fimmu.2018.01957

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