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Upregulation of Nrf2 and Decreased Redox Signaling Contribute to Renoprotective Effects of Chemerin Receptor Blockade in Diabetic Mice

Chemerin, acting through its receptor ChemR23, is an adipokine associated with inflammatory response, glucose and lipid metabolism and vascular function. Although this adipokine has been associated with the development and progression of kidney disease, it is not clear whether the chemerin/ChemR23 s...

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Detalles Bibliográficos
Autores principales: Neves, Karla Bianca, Montezano, Augusto Cesar, Alves-Lopes, Rheure, Bruder-Nascimento, Thiago, Costa, Rafael Menezes, Costa, Roberto S, Touyz, Rhian M, Tostes, Rita C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121242/
https://www.ncbi.nlm.nih.gov/pubmed/30126255
http://dx.doi.org/10.3390/ijms19082454