Antibody to Marinobufagenin Reverses Placenta-Induced Fibrosis of Umbilical Arteries in Preeclampsia

Background: Previous studies implicated cardiotonic steroids, including Na/K-ATPase inhibitor marinobufagenin (MBG), in the pathogenesis of preeclampsia (PE). Immunoneutralization of heightened MBG by Digibind, a digoxin antibody, reduces blood pressure (BP) in patients with PE, and anti-MBG monoclo...

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Detalles Bibliográficos
Autores principales: Fedorova, Olga V., Ishkaraeva, Valentina V., Grigorova, Yulia N., Reznik, Vitaly A., Kolodkin, Nikolai I., Zazerskaya, Irina E., Zernetkina, Valentina, Agalakova, Natalia I., Tapilskaya, Natalia I., Adair, C. David, Lakatta, Edward G., Bagrov, Alexei Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121256/
https://www.ncbi.nlm.nih.gov/pubmed/30104471
http://dx.doi.org/10.3390/ijms19082377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121256/
https://www.ncbi.nlm.nih.gov/pubmed/30104471
http://dx.doi.org/10.3390/ijms19082377

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