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β-Adrenoceptors Trigger Melatonin Synthesis in Phagocytes

Melatonin (5-methoxy-N-acetylserotonin), the pineal hormone, is also synthesized by immune-competent cells. The pineal hormone signals darkness, while melatonin synthesized on demand by activated macrophages at any hour of the day acts locally, favoring regulatory/tolerant phenotypes. Activation of...

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Detalles Bibliográficos
Autores principales: Pires-Lapa, Marco A., Carvalho-Sousa, Claudia E., Cecon, Erika, Fernandes, Pedro A., Markus, Regina P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121262/
https://www.ncbi.nlm.nih.gov/pubmed/30049944
http://dx.doi.org/10.3390/ijms19082182