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The Timing of Melatonin Administration Is Crucial for Its Antidepressant-Like Effect in Mice

Melatonin is synthesized by the pineal gland with a circadian rhythm in synchrony with the environmental light/dark cycle. A gradual increase in circulating levels of melatonin occur after lights off, reaching its maximum around the middle of the dark phase. Agonists of melatonin receptors have prov...

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Detalles Bibliográficos
Autores principales: Estrada-Reyes, Rosa, Valdés-Tovar, Marcela, Arrieta-Baez, Daniel, Dorantes-Barrón, Ana María, Quero-Chávez, Daniel, Solís-Chagoyán, Héctor, Argueta, Jesús, Dubocovich, Margarita L., Benítez-King, Gloria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121277/
https://www.ncbi.nlm.nih.gov/pubmed/30081472
http://dx.doi.org/10.3390/ijms19082278