Cargando…
The Timing of Melatonin Administration Is Crucial for Its Antidepressant-Like Effect in Mice
Melatonin is synthesized by the pineal gland with a circadian rhythm in synchrony with the environmental light/dark cycle. A gradual increase in circulating levels of melatonin occur after lights off, reaching its maximum around the middle of the dark phase. Agonists of melatonin receptors have prov...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121277/ https://www.ncbi.nlm.nih.gov/pubmed/30081472 http://dx.doi.org/10.3390/ijms19082278 |