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Gene Suppression of Transketolase-Like Protein 1 (TKTL1) Sensitizes Glioma Cells to Hypoxia and Ionizing Radiation

In several tumor entities, transketolase-like protein 1 (TKTL1) has been suggested to promote the nonoxidative part of the pentose phosphate pathway (PPP) and thereby to contribute to a malignant phenotype. However, its role in glioma biology has only been sparsely documented. In the present in vitr...

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Detalles Bibliográficos
Autores principales: Heller, Sonja, Maurer, Gabriele D., Wanka, Christina, Hofmann, Ute, Luger, Anna-Luisa, Bruns, Ines, Steinbach, Joachim P., Rieger, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121283/
https://www.ncbi.nlm.nih.gov/pubmed/30044385
http://dx.doi.org/10.3390/ijms19082168