Restraining Akt1 Phosphorylation Attenuates the Repair of Radiation-Induced DNA Double-Strand Breaks and Reduces the Survival of Irradiated Cancer Cells

The survival kinase protein kinase B (Akt) participates in the regulation of essential subcellular processes, e.g., proliferation, growth, survival, and apoptosis, and has a documented role in promoting resistance against genotoxic stress including radiotherapy, presumably by influencing the DNA dam...

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Detalles Bibliográficos
Autores principales: Szymonowicz, Klaudia, Oeck, Sebastian, Krysztofiak, Adam, van der Linden, Jansje, Iliakis, George, Jendrossek, Verena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121313/
https://www.ncbi.nlm.nih.gov/pubmed/30065170
http://dx.doi.org/10.3390/ijms19082233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121313/
https://www.ncbi.nlm.nih.gov/pubmed/30065170
http://dx.doi.org/10.3390/ijms19082233

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