Pharmacological Inhibition of p38 MAPK by SB203580 Increases Resistance to Carboplatin in A2780cp Cells and Promotes Growth in Primary Ovarian Cancer Cells

Chemoresistance renders current chemotherapy regimens ineffective against advanced epithelial ovarian cancer (EOC). Carboplatin (the first-line chemotherapeutic agent to treat EOC) induces cell death by regulating multiple signaling pathways. The objective of this study is to identify the signaling...

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Detalles Bibliográficos
Autores principales: Han, Xiaolu, Chen, Huachen, Zhou, Jiesi, Steed, Helen, Postovit, Lynne-Marie, Fu, YangXin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121386/
https://www.ncbi.nlm.nih.gov/pubmed/30049957
http://dx.doi.org/10.3390/ijms19082184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121386/
https://www.ncbi.nlm.nih.gov/pubmed/30049957
http://dx.doi.org/10.3390/ijms19082184

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