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Investigations of the Copper Peptide Hepcidin-25 by LC-MS/MS and NMR (+)

Hepcidin-25 was identified as the main iron regulator in the human body, and it by binds to the sole iron-exporter ferroportin. Studies showed that the N-terminus of hepcidin is responsible for this interaction, the same N-terminus that encompasses a small copper(II)-binding site known as the ATCUN...

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Detalles Bibliográficos
Autores principales: Abbas, Ioana M., Vranic, Marija, Hoffmann, Holger, El-Khatib, Ahmed H., Montes-Bayón, María, Möller, Heiko M., Weller, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121404/
https://www.ncbi.nlm.nih.gov/pubmed/30072660
http://dx.doi.org/10.3390/ijms19082271