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Investigations of the Copper Peptide Hepcidin-25 by LC-MS/MS and NMR (+)
Hepcidin-25 was identified as the main iron regulator in the human body, and it by binds to the sole iron-exporter ferroportin. Studies showed that the N-terminus of hepcidin is responsible for this interaction, the same N-terminus that encompasses a small copper(II)-binding site known as the ATCUN...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121404/ https://www.ncbi.nlm.nih.gov/pubmed/30072660 http://dx.doi.org/10.3390/ijms19082271 |