Recent Advances by In Silico and In Vitro Studies of Amyloid-β 1-42 Fibril Depicted a S-Shape Conformation

The amyloid-β 1-42 (Aβ1-42) peptide is produced by proteolytic cleavage of the amyloid precursor protein (APP) by sequential reactions that are catalyzed by γ and β secretases. Aβ1-42, together with the Tau protein are two principal hallmarks of Alzheimer’s disease (AD) that are related to disease g...

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Detalles Bibliográficos
Autores principales: Villalobos Acosta, Daniel Miguel Ángel, Chimal Vega, Brenda, Correa Basurto, José, Fragoso Morales, Leticia Guadalupe, Rosales Hernández, Martha Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121414/
https://www.ncbi.nlm.nih.gov/pubmed/30115846
http://dx.doi.org/10.3390/ijms19082415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121414/
https://www.ncbi.nlm.nih.gov/pubmed/30115846
http://dx.doi.org/10.3390/ijms19082415

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