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Recent Advances by In Silico and In Vitro Studies of Amyloid-β 1-42 Fibril Depicted a S-Shape Conformation

The amyloid-β 1-42 (Aβ1-42) peptide is produced by proteolytic cleavage of the amyloid precursor protein (APP) by sequential reactions that are catalyzed by γ and β secretases. Aβ1-42, together with the Tau protein are two principal hallmarks of Alzheimer’s disease (AD) that are related to disease g...

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Detalles Bibliográficos
Autores principales:	Villalobos Acosta, Daniel Miguel Ángel, Chimal Vega, Brenda, Correa Basurto, José, Fragoso Morales, Leticia Guadalupe, Rosales Hernández, Martha Cecilia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121414/ https://www.ncbi.nlm.nih.gov/pubmed/30115846 http://dx.doi.org/10.3390/ijms19082415

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