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Cellular Pharmacology of Palladinum(III) Hematoporphyrin IX Complexes: Solution Stability, Antineoplastic and Apoptogenic Activity, DNA Binding, and Processing of DNA-Adducts

Two paramagnetic Pd(III) complexes of hematoporphyrin IX ((7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-21H-23H-porphyn-2,18-dipropionic acid), Hp), namely a dinuclear one [Pd(III)(2)(Hp(-3H))Cl(3)(H(2)O)(5)]·2PdCl(2), Pd1 and a mononuclear metalloporphyrin type [Pd(III)(Hp(-2H))Cl(H(2)O)]·H(2)O,...

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Detalles Bibliográficos
Autores principales: Momekov, Georgi, Ugrinova, Iva, Pasheva, Evdokia, Tsekova, Daniela, Gencheva, Galina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121444/
https://www.ncbi.nlm.nih.gov/pubmed/30126243
http://dx.doi.org/10.3390/ijms19082451