Prostanoid EP(2) Receptors Are Up-Regulated in Human Pulmonary Arterial Hypertension: A Key Anti-Proliferative Target for Treprostinil in Smooth Muscle Cells

Prostacyclins are extensively used to treat pulmonary arterial hypertension (PAH), a life-threatening disease involving the progressive thickening of small pulmonary arteries. Although these agents are considered to act therapeutically via the prostanoid IP receptor, treprostinil is the only prostac...

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Detalles Bibliográficos
Autores principales: Patel, Jigisha A., Shen, Lei, Hall, Susan M., Benyahia, Chabha, Norel, Xavier, McAnulty, Robin J., Moledina, Shahin, Silverstein, Adam M., Whittle, Brendan J., Clapp, Lucie H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121445/
https://www.ncbi.nlm.nih.gov/pubmed/30103548
http://dx.doi.org/10.3390/ijms19082372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121445/
https://www.ncbi.nlm.nih.gov/pubmed/30103548
http://dx.doi.org/10.3390/ijms19082372

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