Cargando…
Prostanoid EP(2) Receptors Are Up-Regulated in Human Pulmonary Arterial Hypertension: A Key Anti-Proliferative Target for Treprostinil in Smooth Muscle Cells
Prostacyclins are extensively used to treat pulmonary arterial hypertension (PAH), a life-threatening disease involving the progressive thickening of small pulmonary arteries. Although these agents are considered to act therapeutically via the prostanoid IP receptor, treprostinil is the only prostac...
Autores principales: | Patel, Jigisha A., Shen, Lei, Hall, Susan M., Benyahia, Chabha, Norel, Xavier, McAnulty, Robin J., Moledina, Shahin, Silverstein, Adam M., Whittle, Brendan J., Clapp, Lucie H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121445/ https://www.ncbi.nlm.nih.gov/pubmed/30103548 http://dx.doi.org/10.3390/ijms19082372 |
Ejemplares similares
-
Prostanoid Receptors in the Human Vascular Wall
por: Norel, Xavier
Publicado: (2007) -
Decreased PGE(2) Content Reduces MMP-1 Activity and Consequently Increases Collagen Density in Human Varicose Vein
por: Gomez, Ingrid, et al.
Publicado: (2014) -
EP4-mediated prostanoid signalling promotes oral cancer progression
por: Sapienza, Karen, et al.
Publicado: (2010) -
E-type prostanoid receptor 4 (EP4) in disease and therapy
por: Konya, Viktoria, et al.
Publicado: (2013) -
Improved homology modeling of the human & rat EP(4) prostanoid receptors
por: Holt, Melissa C., et al.
Publicado: (2019)