Prostanoid EP(2) Receptors Are Up-Regulated in Human Pulmonary Arterial Hypertension: A Key Anti-Proliferative Target for Treprostinil in Smooth Muscle Cells

Prostacyclins are extensively used to treat pulmonary arterial hypertension (PAH), a life-threatening disease involving the progressive thickening of small pulmonary arteries. Although these agents are considered to act therapeutically via the prostanoid IP receptor, treprostinil is the only prostac...

Descripción completa

Detalles Bibliográficos
Autores principales: Patel, Jigisha A., Shen, Lei, Hall, Susan M., Benyahia, Chabha, Norel, Xavier, McAnulty, Robin J., Moledina, Shahin, Silverstein, Adam M., Whittle, Brendan J., Clapp, Lucie H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121445/
https://www.ncbi.nlm.nih.gov/pubmed/30103548
http://dx.doi.org/10.3390/ijms19082372

Ejemplares similares

Ejemplares similares