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Mechanisms of PKA-Dependent Potentiation of Kv7.5 Channel Activity in Human Airway Smooth Muscle Cells

β-adrenergic receptor (βAR) activation promotes relaxation of both vascular and airway smooth muscle cells (VSMCs and ASMCs, respectively), though the signaling mechanisms have not been fully elucidated. We previously found that the activity of Kv7.5 voltage-activated potassium channels in VSMCs is...

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Detalles Bibliográficos
Autores principales: Brueggemann, Lyubov I., Cribbs, Leanne L., Schwartz, Jeffrey, Wang, Minhua, Kouta, Ahmed, Byron, Kenneth L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121446/
https://www.ncbi.nlm.nih.gov/pubmed/30061510
http://dx.doi.org/10.3390/ijms19082223