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Immune Cell Induced Migration of Osteoprogenitor Cells Is Mediated by TGF-β Dependent Upregulation of NOX4 and Activation of Focal Adhesion Kinase

The cytokines secreted by immune cells have a large impact on the tissue, surrounding a fracture, e.g., by attraction of osteoprogenitor cells. However, the underlying mechanisms are not yet fully understood. Thus, this study aims at investigating molecular mechanisms of the immune cell-mediated mig...

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Detalles Bibliográficos
Autores principales: Ehnert, Sabrina, Linnemann, Caren, Aspera-Werz, Romina H., Bykova, Daria, Biermann, Sara, Fecht, Leonie, De Zwart, Peter M., Nussler, Andreas K., Stuby, Fabian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121453/
https://www.ncbi.nlm.nih.gov/pubmed/30065198
http://dx.doi.org/10.3390/ijms19082239