Cargando…
Immune Cell Induced Migration of Osteoprogenitor Cells Is Mediated by TGF-β Dependent Upregulation of NOX4 and Activation of Focal Adhesion Kinase
The cytokines secreted by immune cells have a large impact on the tissue, surrounding a fracture, e.g., by attraction of osteoprogenitor cells. However, the underlying mechanisms are not yet fully understood. Thus, this study aims at investigating molecular mechanisms of the immune cell-mediated mig...
Autores principales: | Ehnert, Sabrina, Linnemann, Caren, Aspera-Werz, Romina H., Bykova, Daria, Biermann, Sara, Fecht, Leonie, De Zwart, Peter M., Nussler, Andreas K., Stuby, Fabian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121453/ https://www.ncbi.nlm.nih.gov/pubmed/30065198 http://dx.doi.org/10.3390/ijms19082239 |
Ejemplares similares
-
Exposure to 16 Hz Pulsed Electromagnetic Fields Protect the Structural Integrity of Primary Cilia and Associated TGF-β Signaling in Osteoprogenitor Cells Harmed by Cigarette Smoke
por: Chen, Yangmengfan, et al.
Publicado: (2021) -
Donor Site Location Is Critical for Proliferation, Stem Cell Capacity, and Osteogenic Differentiation of Adipose Mesenchymal Stem/Stromal Cells: Implications for Bone Tissue Engineering
por: Reumann, Marie K., et al.
Publicado: (2018) -
Nicotine and Cotinine Induce Neutrophil Extracellular Trap Formation—Potential Risk for Impaired Wound Healing in Smokers
por: Aspera-Werz, Romina H., et al.
Publicado: (2022) -
Use of in vitro bone models to screen for altered bone metabolism, osteopathies, and fracture healing: challenges of complex models
por: Ehnert, Sabrina, et al.
Publicado: (2020) -
Cigarette Smoke Induces the Risk of Metabolic Bone Diseases: Transforming Growth Factor Beta Signaling Impairment via Dysfunctional Primary Cilia Affects Migration, Proliferation, and Differentiation of Human Mesenchymal Stem Cells
por: Aspera-Werz, Romina H., et al.
Publicado: (2019)