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Environmental Carcinogenesis and Transgenerational Transmission of Carcinogenic Risk: From Genetics to Epigenetics

The dominant pathogenic model, somatic mutation theory (SMT), considers carcinogenesis as a ‘genetic accident’ due to the accumulation of ‘stochastic’ DNA mutations. This model was proposed and accepted by the scientific community when cancer mainly affected the elderly, but it does not explain the...

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Detalles Bibliográficos
Autores principales: Burgio, Ernesto, Piscitelli, Prisco, Colao, Annamaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121489/
https://www.ncbi.nlm.nih.gov/pubmed/30127322
http://dx.doi.org/10.3390/ijerph15081791