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The Regulation and Function of the L-Type Amino Acid Transporter 1 (LAT1) in Cancer

The progression of cancer is associated with increases in amino acid uptake by cancer cells. Upon their entry into cells through specific transporters, exogenous amino acids are used to synthesize proteins, nucleic acids and lipids and to generate ATP. The essential amino acid leucine is also import...

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Detalles Bibliográficos
Autores principales: Salisbury, Travis B, Arthur, Subha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121554/
https://www.ncbi.nlm.nih.gov/pubmed/30103560
http://dx.doi.org/10.3390/ijms19082373