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The Regulation and Function of the L-Type Amino Acid Transporter 1 (LAT1) in Cancer
The progression of cancer is associated with increases in amino acid uptake by cancer cells. Upon their entry into cells through specific transporters, exogenous amino acids are used to synthesize proteins, nucleic acids and lipids and to generate ATP. The essential amino acid leucine is also import...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121554/ https://www.ncbi.nlm.nih.gov/pubmed/30103560 http://dx.doi.org/10.3390/ijms19082373 |