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Using Persistent Homology as a New Approach for Super-Resolution Localization Microscopy Data Analysis and Classification of γH2AX Foci/Clusters

DNA double strand breaks (DSB) are the most severe damages in chromatin induced by ionizing radiation. In response to such environmentally determined stress situations, cells have developed repair mechanisms. Although many investigations have contributed to a detailed understanding of repair process...

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Detalles Bibliográficos
Autores principales: Hofmann, Andreas, Krufczik, Matthias, Heermann, Dieter W., Hausmann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121565/
https://www.ncbi.nlm.nih.gov/pubmed/30072594
http://dx.doi.org/10.3390/ijms19082263