Unique Ca(2+)-Cycling Protein Abundance and Regulation Sustains Local Ca(2+) Releases and Spontaneous Firing of Rabbit Sinoatrial Node Cells

Spontaneous beating of the heart pacemaker, the sinoatrial node, is generated by sinoatrial node cells (SANC) and caused by gradual change of the membrane potential called diastolic depolarization (DD). Submembrane local Ca(2+) releases (LCR) from sarcoplasmic reticulum (SR) occur during late DD and...

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Detalles Bibliográficos
Autores principales: Vinogradova, Tatiana M., Tagirova (Sirenko), Syevda, Lakatta, Edward G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121616/
https://www.ncbi.nlm.nih.gov/pubmed/30044420
http://dx.doi.org/10.3390/ijms19082173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121616/
https://www.ncbi.nlm.nih.gov/pubmed/30044420
http://dx.doi.org/10.3390/ijms19082173

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