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Unique Ca(2+)-Cycling Protein Abundance and Regulation Sustains Local Ca(2+) Releases and Spontaneous Firing of Rabbit Sinoatrial Node Cells
Spontaneous beating of the heart pacemaker, the sinoatrial node, is generated by sinoatrial node cells (SANC) and caused by gradual change of the membrane potential called diastolic depolarization (DD). Submembrane local Ca(2+) releases (LCR) from sarcoplasmic reticulum (SR) occur during late DD and...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121616/ https://www.ncbi.nlm.nih.gov/pubmed/30044420 http://dx.doi.org/10.3390/ijms19082173 |