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A Short Half-Life α(IIb)β(3) Antagonist ANTP266 Reduces Thrombus Formation

Integrin α(IIb)β(3) plays a pivotal role in platelet aggregation. Three α(IIb)β(3) antagonists have been approved by the Food and Drug Administration (FDA) for the treatment of cardiovascular diseases. Unfortunately, all of these three drugs can cause the side effect of severe bleeding. Therefore, d...

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Detalles Bibliográficos
Autores principales: Liu, Tong-Dan, Ren, Shen-Hong, Ding, Xue, Xie, Zhou-Ling, Kong, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121621/
https://www.ncbi.nlm.nih.gov/pubmed/30082659
http://dx.doi.org/10.3390/ijms19082306