PEI-Coated Fe(3)O(4) Nanoparticles Enable Efficient Delivery of Therapeutic siRNA Targeting REST into Glioblastoma Cells

Glioblastomas (GBM) are the most frequent brain tumors lacking efficient treatment. The increasingly elucidated gene targets make siRNA-based gene therapy a promising anticancer approach, while an efficient delivery system is urgently needed. Here, polyethyleneimine (PEI)-coated Fe(3)O(4) nanopartic...

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Detalles Bibliográficos
Autores principales: Wang, Rui, Degirmenci, Volkan, Xin, Hongchuan, Li, Ying, Wang, Liping, Chen, Jiayu, Hu, Xiaoyu, Zhang, Dianbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121642/
https://www.ncbi.nlm.nih.gov/pubmed/30065155
http://dx.doi.org/10.3390/ijms19082230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121642/
https://www.ncbi.nlm.nih.gov/pubmed/30065155
http://dx.doi.org/10.3390/ijms19082230

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