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PEI-Coated Fe(3)O(4) Nanoparticles Enable Efficient Delivery of Therapeutic siRNA Targeting REST into Glioblastoma Cells
Glioblastomas (GBM) are the most frequent brain tumors lacking efficient treatment. The increasingly elucidated gene targets make siRNA-based gene therapy a promising anticancer approach, while an efficient delivery system is urgently needed. Here, polyethyleneimine (PEI)-coated Fe(3)O(4) nanopartic...
Autores principales: | Wang, Rui, Degirmenci, Volkan, Xin, Hongchuan, Li, Ying, Wang, Liping, Chen, Jiayu, Hu, Xiaoyu, Zhang, Dianbao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121642/ https://www.ncbi.nlm.nih.gov/pubmed/30065155 http://dx.doi.org/10.3390/ijms19082230 |
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