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Implications of Metal Binding and Asparagine Deamidation for Amyloid Formation

Increasing evidence suggests that amyloid formation, i.e., self-assembly of proteins and the resulting conformational changes, is linked with the pathogenesis of various neurodegenerative disorders such as Alzheimer’s disease, prion diseases, and Lewy body diseases. Among the factors that accelerate...

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Detalles Bibliográficos
Autores principales: Sadakane, Yutaka, Kawahara, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121660/
https://www.ncbi.nlm.nih.gov/pubmed/30126231
http://dx.doi.org/10.3390/ijms19082449