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Implications of Metal Binding and Asparagine Deamidation for Amyloid Formation
Increasing evidence suggests that amyloid formation, i.e., self-assembly of proteins and the resulting conformational changes, is linked with the pathogenesis of various neurodegenerative disorders such as Alzheimer’s disease, prion diseases, and Lewy body diseases. Among the factors that accelerate...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121660/ https://www.ncbi.nlm.nih.gov/pubmed/30126231 http://dx.doi.org/10.3390/ijms19082449 |