Early Developmental Exposure to General Anesthetic Agents in Primary Neuron Culture Disrupts Synapse Formation via Actions on the mTOR Pathway

Human epidemiologic studies and laboratory investigations in animal models suggest that exposure to general anesthetic agents (GAs) have harmful effects on brain development. The mechanism underlying this putative iatrogenic condition is not clear and there are currently no accepted strategies for p...

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Detalles Bibliográficos
Autores principales: Xu, Jing, Mathena, R. Paige, Xu, Michael, Wang, YuChia, Chang, CheJui, Fang, Yiwen, Zhang, Pengbo, Mintz, C. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121894/
https://www.ncbi.nlm.nih.gov/pubmed/30049952
http://dx.doi.org/10.3390/ijms19082183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121894/
https://www.ncbi.nlm.nih.gov/pubmed/30049952
http://dx.doi.org/10.3390/ijms19082183

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