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Omega-6 oxylipins generated by soluble epoxide hydrolase are associated with knee osteoarthritis

Omega-6 FAs are inflammatory mediators that are increased in joints with osteoarthritis (OA), but their association with OA progression is not yet well defined. To investigate the relationship between omega-6 FAs and knee OA, we measured with LC-MS the levels of 22 omega-6 lipids (arachidonic acid,...

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Detalles Bibliográficos
Autores principales: Valdes, Ana M., Ravipati, Srinivasarao, Pousinis, Petros, Menni, Cristina, Mangino, Massimo, Abhishek, Abhishek, Chapman, Victoria, Barrett, David A., Doherty, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121933/
https://www.ncbi.nlm.nih.gov/pubmed/29986999
http://dx.doi.org/10.1194/jlr.P085118