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The Generation of CAR-Transfected Natural Killer T Cells for the Immunotherapy of Melanoma

Natural killer T (NKT) cells represent a cell subpopulation that combines characteristics of natural killer (NK) cells and T cells. Through their endogenous T-cell receptors (TCRs), they reveal a pronounced intrinsic anti-tumor activity. Thus, a NKT cell transfected with a chimeric antigen receptor...

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Detalles Bibliográficos
Autores principales: Simon, Bianca, Wiesinger, Manuel, März, Johannes, Wistuba-Hamprecht, Kilian, Weide, Benjamin, Schuler-Thurner, Beatrice, Schuler, Gerold, Dörrie, Jan, Uslu, Ugur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121949/
https://www.ncbi.nlm.nih.gov/pubmed/30103488
http://dx.doi.org/10.3390/ijms19082365