Calcitriol and Calcidiol Can Sensitize Melanoma Cells to Low–LET Proton Beam Irradiation

Proton beam irradiation promises therapeutic utility in the management of uveal melanoma. Calcitriol (1,25(OH)(2)D(3))—the biologically active metabolite of vitamin D(3)—and its precursor, calcidiol (25(OH)D(3)), exert pleiotropic effects on melanoma cells. The aim of the study was to evaluate the e...

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Detalles Bibliográficos
Autores principales: Podgorska, Ewa, Drzal, Agnieszka, Matuszak, Zenon, Swakon, Jan, Slominski, Andrzej, Elas, Martyna, Urbanska, Krystyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122082/
https://www.ncbi.nlm.nih.gov/pubmed/30065179
http://dx.doi.org/10.3390/ijms19082236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122082/
https://www.ncbi.nlm.nih.gov/pubmed/30065179
http://dx.doi.org/10.3390/ijms19082236

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