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Calcitriol and Calcidiol Can Sensitize Melanoma Cells to Low–LET Proton Beam Irradiation
Proton beam irradiation promises therapeutic utility in the management of uveal melanoma. Calcitriol (1,25(OH)(2)D(3))—the biologically active metabolite of vitamin D(3)—and its precursor, calcidiol (25(OH)D(3)), exert pleiotropic effects on melanoma cells. The aim of the study was to evaluate the e...
Autores principales: | Podgorska, Ewa, Drzal, Agnieszka, Matuszak, Zenon, Swakon, Jan, Slominski, Andrzej, Elas, Martyna, Urbanska, Krystyna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122082/ https://www.ncbi.nlm.nih.gov/pubmed/30065179 http://dx.doi.org/10.3390/ijms19082236 |
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