A Naturally-Occurring Dominant-Negative Inhibitor of Keap1 Competitively against Its Negative Regulation of Nrf2

Transcription factor Nrf2 (nuclear factor-erythroid 2-related factor 2) is a master regulator of antioxidant and/or electrophile response elements (AREs/EpREs)-driven genes involved in homeostasis, detoxification, and adaptation to various stresses. The cytoprotective activity of Nrf2, though being...

Descripción completa

Detalles Bibliográficos
Autores principales: Qiu, Lu, Wang, Meng, Zhu, Yuping, Xiang, Yuancai, Zhang, Yiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122090/
https://www.ncbi.nlm.nih.gov/pubmed/30042301
http://dx.doi.org/10.3390/ijms19082150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122090/
https://www.ncbi.nlm.nih.gov/pubmed/30042301
http://dx.doi.org/10.3390/ijms19082150

Ejemplares similares