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A Naturally-Occurring Dominant-Negative Inhibitor of Keap1 Competitively against Its Negative Regulation of Nrf2
Transcription factor Nrf2 (nuclear factor-erythroid 2-related factor 2) is a master regulator of antioxidant and/or electrophile response elements (AREs/EpREs)-driven genes involved in homeostasis, detoxification, and adaptation to various stresses. The cytoprotective activity of Nrf2, though being...
Autores principales: | Qiu, Lu, Wang, Meng, Zhu, Yuping, Xiang, Yuancai, Zhang, Yiguo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122090/ https://www.ncbi.nlm.nih.gov/pubmed/30042301 http://dx.doi.org/10.3390/ijms19082150 |
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