Cargando…

Cobalt-catalyzed nucleophilic addition of the allylic C(sp(3))–H bond of simple alkenes to ketones

We herein describe a cobalt/Xantphos-catalyzed regioselective addition of simple alkenes to acetophenone derivatives, affording branched homoallylic alcohols in high yields with perfect branch selectivities. The intermediate of the reaction would be a nucleophilic allylcobalt(I) species generated vi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mita, Tsuyoshi, Uchiyama, Masashi, Michigami, Kenichi, Sato, Yoshihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2018
Materias:	Letter
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122116/ https://www.ncbi.nlm.nih.gov/pubmed/30202455 http://dx.doi.org/10.3762/bjoc.14.176

Ejemplares similares

Cobalt-Catalyzed, Aminoquinoline-Directed Coupling of sp(2) C–H Bonds with Alkenes
por: Grigorjeva, Liene, et al.
Publicado: (2014)

The syn/anti-Dichotomy in the Palladium-Catalyzed Addition of Nucleophiles to Alkenes
por: Kočovský, Pavel, et al.
Publicado: (2015)

Gold(I)‐Catalyzed Nucleophilic Allylation of Azinium Ions with Allylboronates
por: O'Brien, Luke, et al.
Publicado: (2022)

Pyridylic anions are soft nucleophiles in the palladium-catalyzed C(sp(3))–H allylation of 4-alkylpyridines
por: Wasfy, Nour, et al.
Publicado: (2020)

Nickel-catalyzed asymmetric reductive aryl-allylation of unactivated alkenes
por: Lin, Zhiyang, et al.
Publicado: (2021)

Boron-Catalyzed, Diastereo- and Enantioselective Allylation of Ketones with Allenes
por: Nicholson, Kieran, et al.
Publicado: (2022)

The Isomerization of Allylrhodium Intermediates in the Rhodium-Catalyzed Nucleophilic Allylation of Cyclic Imines**
por: Hepburn, Hamish B, et al.
Publicado: (2014)

Palladium-catalyzed asymmetric allylic alkylation (AAA) with alkyl sulfones as nucleophiles
por: Trost, Barry M., et al.
Publicado: (2021)

Organozinc pivalates for cobalt-catalyzed difluoroalkylarylation of alkenes
por: Cheng, Xinyi, et al.
Publicado: (2021)

Ligand-promoted cobalt-catalyzed radical hydroamination of alkenes
por: Shen, Xuzhong, et al.
Publicado: (2020)

Cobalt-catalyzed multisubstituted allylation of the chelation-assisted C–H bond of (hetero)arenes with cyclopropenes
por: Ramachandran, Kuppan, et al.
Publicado: (2021)

Iridium-catalyzed asymmetric ring-opening reactions of oxabicyclic alkenes with secondary amine nucleophiles
por: Yang, Dingqiao, et al.
Publicado: (2009)

Copper-Catalyzed Oxidative Dehydrogenative Carboxylation of Unactivated Alkanes to Allylic Esters via Alkenes
por: Tran, Ba L., et al.
Publicado: (2014)

Chain Walking of Allylrhodium Species Towards Esters During Rhodium‐Catalyzed Nucleophilic Allylations of Imines
por: Martínez, Jose I., et al.
Publicado: (2015)

Nickel-catalyzed direct stereoselective α-allylation of ketones with non-conjugated dienes
por: Cao, Yi-Xuan, et al.
Publicado: (2023)

Cobalt catalyzed carbonylation of unactivated C(sp(3))–H bonds
por: Barsu, Nagaraju, et al.
Publicado: (2017)

Iron-Catalyzed Coupling of Alkenes and Enones: Sakurai–Michael-type Conjugate Addition of Catalytic Allyliron Nucleophiles
por: Scrivener, Sarah G., et al.
Publicado: (2023)

Nickel-catalyzed allylic defluorinative alkylation of trifluoromethyl alkenes with reductive decarboxylation of redox-active esters
por: Lu, Xi, et al.
Publicado: (2018)

The Allylic Alkylation of Ketone Enolates
por: Junk, Lukas, et al.
Publicado: (2020)

Enantioselective Cobalt-Catalyzed Hydroboration of Fluoroalkyl-Substituted Alkenes to Access Chiral Fluoroalkylboronates
por: Hu, Ming, et al.
Publicado: (2022)

A New Palladium-Catalyzed Phenyl-Alkene Bond Formation
por: Schmor, Brad, et al.
Publicado: (2002)

Iodine-catalyzed synthesis of benzoxazoles using catechols, ammonium acetate, and alkenes/alkynes/ketones via C–C and C–O bond cleavage
por: Aboonajmi, Jasem, et al.
Publicado: (2022)

General Allylic C–H Alkylation with Tertiary Nucleophiles
por: Howell, Jennifer M., et al.
Publicado: (2014)

Cobalt-Catalyzed Efficient Asymmetric Hydrogenation of α-Primary Amino Ketones
por: Yang, Huiwen, et al.
Publicado: (2023)

Enantioselective nickel-catalyzed arylative and alkenylative intramolecular 1,2-allylations of tethered allene–ketones
por: Di Sanza, Riccardo, et al.
Publicado: (2020)

Difunctionalization of Alkenes and Alkynes via Intermolecular Radical and Nucleophilic Additions
por: Yao, Hongjun, et al.
Publicado: (2020)

Cobalt-Catalyzed E-Selective Isomerization of Alkenes with a Phosphine-Amido-Oxazoline Ligand
por: Liu, Hongmei, et al.
Publicado: (2020)

Pd-catalyzed asymmetric allylic substitution cascade using α-(pyridin-1-yl)-acetamides formed in situ as nucleophiles
por: Yao, Kun, et al.
Publicado: (2018)

Cu-catalyzed C–C bond formation of vinylidene cyclopropanes with carbon nucleophiles
por: Chen, Jichao, et al.
Publicado: (2019)

Catalytic asymmetric allylation of aldehydes with alkenes through allylic C(sp(3))–H functionalization mediated by organophotoredox and chiral chromium hybrid catalysis
por: Mitsunuma, Harunobu, et al.
Publicado: (2019)

Allylic Amination of Alkenes with Iminothianthrenes to Afford Alkyl Allylamines
por: Cheng, Qiang, et al.
Publicado: (2020)

Asymmetric synthesis of multifunctional aryl allyl ethers by nucleophilic catalysis
por: Zhao, Shuai, et al.
Publicado: (2019)

Diastereo- and Enantioselective Iridium-Catalyzed Allylation of Cyclic Ketone Enolates: Synergetic Effect of Ligands and Barium Enolates
por: Chen, Wenyong, et al.
Publicado: (2014)

One-Pot Conversion of Allylic Alcohols to α-Methyl Ketones via Iron-Catalyzed Isomerization–Methylation
por: Latham, Daniel E., et al.
Publicado: (2019)

Cobalt-catalyzed deoxygenative triborylation of allylic ethers to access 1,1,3-triborylalkanes
por: Teo, Wei Jie, et al.
Publicado: (2020)

Computational insights into Ir(iii)-catalyzed allylic C–H amination of terminal alkenes: mechanism, regioselectivity, and catalytic activity
por: Pan, Deng, et al.
Publicado: (2021)

Cobalt-Catalyzed Methoxycarbonylation of Substituted Dichlorobenzenes as an Example of a Facile Radical Anion Nucleophilic Substitution in Chloroarenes
por: Khaibulova, Tatyana S., et al.
Publicado: (2014)

Correction: Cu-catalyzed C–C bond formation of vinylidene cyclopropanes with carbon nucleophiles
por: Chen, Jichao, et al.
Publicado: (2020)

Cobalt-catalyzed difluoroalkylation of tertiary aryl ketones for facile synthesis of quaternary alkyl difluorides
por: Li, Chao, et al.
Publicado: (2018)

Metabolism of alkenes and ketones by Candida maltosa and related yeasts
por: Beier, Andy, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_iq4nn4ip73ktmd7qg327u64j2d