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Decreased expression of microRNA-214 contributes to imatinib mesylate resistance of chronic myeloid leukemia patients by upregulating ABCB1 gene expression

The aim of the present study was to determine the expression of adenosine triphosphate binding cassette subfamily B member 1 (ABCB1) gene and its protein P-glycoprotein (PGP) in bone marrow mononuclear cells from chronic myeloid leukemia (CML) patients with imatinib mesylate (IM) resistance, or IM-r...

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Detalles Bibliográficos
Autores principales: Jin, Jing, Yao, Jia, Yue, Fang, Jin, Zhaoying, Li, Dan, Wang, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122133/
https://www.ncbi.nlm.nih.gov/pubmed/30186389
http://dx.doi.org/10.3892/etm.2018.6404