DNA hypermethylation-mediated downregulation of antioxidant genes contributes to the early onset of cataracts in highly myopic eyes

High myopia is recognized as a risk factor for earlier onset of nuclear cataracts. One possible explanation for this is that lenses in highly myopic eyes are exposed to higher levels of oxygen than normal eyes owing to earlier vitreous liquefaction and, hence, are subjected to oxidative insults. Her...

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Detalles Bibliográficos
Autores principales: Zhu, Xiangjia, Li, Dan, Du, Yu, He, Wenwen, Lu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122317/
https://www.ncbi.nlm.nih.gov/pubmed/30172102
http://dx.doi.org/10.1016/j.redox.2018.08.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122317/
https://www.ncbi.nlm.nih.gov/pubmed/30172102
http://dx.doi.org/10.1016/j.redox.2018.08.012

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